SCHEMBL15433345

SCHEMBL15433345

C/C(F)=C(\F)c1ccc(C2CCC(C(=O)Oc3cc(F)c(OC(F)(F)F)c(F)c3)CC2)cc1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 2/20 0.33
MAPT P10636 1/20 0.33
POLB P06746 2/20 0.33
HRH3 Q9Y5N1 1/20 0.32
KMT2A Q03164 2/20 0.32
HTT P42858 1/20 0.32
TDP1 Q9NUW8 1/20 0.32
FFAR4 Q5NUL3 1/20 0.31
ATM Q13315 1/20 0.31
FAAH O00519 1/20 0.31
HSD11B1 P28845 2/20 0.31
HSD17B1 P14061 1/20 0.31
HSD17B2 P37059 1/20 0.31
EPHX2 P34913 1/20 0.31
CYP2C9 P11712 2/20 0.31
SCN9A Q15858 1/20 0.31
CYP3A4 P08684 1/20 0.30
KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433727 0.78 FFAR4 (0.36) FFAR4
SCHEMBL15433230 0.75
SCHEMBL15433229 0.72 ALDH1A1 (0.34) SMN1; SMN2ALDH1A1MAPTKMT2AFFAR4
SCHEMBL7903057 0.71 FFAR4 (0.38) SMN1; SMN2POLBKMT2AHTTTDP1
SCHEMBL7066258 0.71 PKM (0.37) MAPTPOLBKMT2AHTTCYP2C9
SCHEMBL7903056 0.71 FFAR4 (0.38) SMN1; SMN2POLBKMT2AHTTTDP1
SCHEMBL7903055 0.71 FFAR4 (0.38) SMN1; SMN2POLBKMT2AHTTTDP1
SCHEMBL15433825 0.71 CYP2C9 (0.35) ALDH1A1MAPTKMT2ACYP2C9
SCHEMBL15433342 0.71 ELANE (0.32) ELANESMN1; SMN2ALDH1A1MAPTPOLB
SCHEMBL15433343 0.70 SENP1 (0.34) SMN1; SMN2ALDH1A1MAPTPOLBKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed