SCHEMBL15433468

SCHEMBL15433468

CCC/C(F)=C(\F)c1ccc(-c2ccc(-c3ccc(-c4cc(F)c(C#N)c(F)c4)c(F)c3)c(F)c2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FASN P49327 1/20 0.37
KDM1A O60341 4/20 0.36
ESR1 P03372 3/20 0.34
ESR2 Q92731 3/20 0.34
RARB P10826 1/20 0.34
PDE10A Q9Y233 2/20 0.32
PRKACA P17612 1/20 0.32
PRKACG P22612 1/20 0.32
PRKACB P22694 1/20 0.32
ALOX5AP P20292 1/20 0.31
FEN1 P39748 1/20 0.31
NPC1 O15118 2/20 0.30
RAB9A P51151 2/20 0.30
MGLL Q99685 1/20 0.30
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
MAPT P10636 1/20 0.30
HPGD P15428 1/20 0.30
KMT2A Q03164 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15433237 0.83 KDM1A (0.38) FASNKDM1AESR1ESR2
SCHEMBL15433386 0.82 RARB (0.39) ESR1RARBNPC1RAB9AMEN1
SCHEMBL15433428 0.81 KIF11 (0.37) RARBALOX5APFEN1NPC1RAB9A
SCHEMBL15433394 0.81 RARB (0.40) ESR1ESR2RARBALOX5APFEN1
SCHEMBL15433536 0.79 RARB (0.50) RARBMEN1ALDH1A1MAPTKMT2A
SCHEMBL15433392 0.78 RARB (0.44) RARBMGLL
SCHEMBL15433163 0.77 TRPV4 (0.37) FASNRARBNPC1RAB9AMEN1
SCHEMBL15433183 0.77 RARB (0.41) ESR1RARBNPC1RAB9AMEN1
SCHEMBL15433498 0.77 RARB (0.41) RARB
SCHEMBL16602469 0.77 MEN1 (0.43) FASNKDM1ARARBPRKACAPRKACG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-8956551-B2 Liquid crystal compound having fluorovinyl group, liquid crystal composition and liquid crystal display device JNC CORPORATION (JP) 2015-02-17 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed
US-20140021406-A1 LIQUID CRYSTAL COMPOUND HAVING FLUOROVINYL GROUP, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE JNC PETROCHEMICAL CORPORATION (JP) 2014-01-23 US disclosed