Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 6/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.44 |
| ▸ | MME | P08473 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 3/20 | 0.43 |
| ▸ | PPARD | Q03181 | 3/20 | 0.43 |
| ▸ | PPARA | Q07869 | 3/20 | 0.43 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.41 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.40 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.40 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.40 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.40 |
| ▸ | GCGR | P47871 | 1/20 | 0.40 |
| ▸ | CTSA | P10619 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15434180 | 0.87 | NPSR1 (0.47) | FFAR4NPSR1FFAR1PPARGPPARD | |
| SCHEMBL15434111 | 0.87 | NPSR1 (0.47) | FFAR4NPSR1FFAR1PPARGPPARD | |
| SCHEMBL15434130 | 0.85 | FFAR1 (0.51) | FFAR4NPSR1FFAR1MMEPPARG | |
| SCHEMBL15434157 | 0.83 | NPSR1 (0.51) | NPSR1FFAR1PPARGPPARDPPARA | |
| SCHEMBL15434117 | 0.82 | NPSR1 (0.49) | FFAR4NPSR1FFAR1PPARGPPARD | |
| SCHEMBL15434119 | 0.81 | NPSR1 (0.51) | FFAR4NPSR1FFAR1PPARGPPARD | |
| SCHEMBL15434172 | 0.81 | FFAR1 (0.49) | FFAR4NPSR1FFAR1MMEPPARG | |
| SCHEMBL2535115 | 0.81 | PTGER4 (0.53) | FFAR4NPSR1FFAR1MMEPTGER1 | |
| SCHEMBL15434163 | 0.80 | PPARG (0.48) | NPSR1FFAR1PPARGPPARDPPARA | |
| SCHEMBL15434147 | 0.80 | FFAR4 (0.49) | FFAR4NPSR1FFAR1MMEPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8633245-B2 | PAI-1 inhibitor | INSTITUTE OF MEDICINAL MOLECULAR DESIGN, INC. (JP) | 2014-01-21 | — | — | US | disclosed |