SCHEMBL15434191

SCHEMBL15434191

CC1(C)c2ccccc2-c2ccc3c(c21)C1(c2ccccc2-c2ccccc21)c1c-3ccc2c1sc1ccccc12

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
PARP14 Q460N5 1/20 0.38
ALOX5 P09917 1/20 0.37
GPR3 P46089 1/20 0.33
PRKDC P78527 4/20 0.32
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15434194 0.91 PARP14 (0.36) PARP14ALOX5GPR3PRKDC
SCHEMBL17694784 0.90 PARP14 (0.42) PARP14ALOX5GPR3PRKDCMAPT
SCHEMBL18156883 0.87 ALOX5 (0.43) PARP14ALOX5GPR3PRKDCMAPT
SCHEMBL22930729 0.85 ALOX5 (0.41) PARP14ALOX5GPR3PRKDCMAPT
SCHEMBL23184370 0.84 PARP14 (0.39) PARP14ALOX5GPR3PRKDCMAPT
SCHEMBL15434264 0.83 KDM4E (0.32) MAPT
SCHEMBL15434279 0.82 PARP14 (0.38) PARP14ALOX5GPR3PRKDCMAPT
SCHEMBL15434193 0.82 MAPT (0.35) GPR3MAPT
SCHEMBL17299430 0.82 PARP14 (0.38) PARP14ALOX5GPR3PRKDCMAPT
SCHEMBL18732421 0.81 PDK2 (0.37) PARP14ALOX5GPR3PRKDCMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2014010910-A1 COMPOUND, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산하이메탈(주) (KR) 2014-01-16 WO disclosed