SCHEMBL22930729

SCHEMBL22930729

c1ccc2c(c1)-c1ccccc1C21c2ccccc2C2(c3ccccc3-c3ccc4c(sc5ccccc54)c32)c2ccccc21

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
PARP14 Q460N5 1/20 0.39
GPR3 P46089 1/20 0.38
MAPT P10636 5/20 0.33
RAB9A P51151 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
PRKDC P78527 7/20 0.33
MEN1 O00255 2/20 0.32
KMT2A Q03164 2/20 0.32
PIK3CD O00329 2/20 0.32
PIK3CB P42338 2/20 0.32
BRD4 O60885 1/20 0.32
PIK3CA P42336 1/20 0.32
MTOR P42345 1/20 0.32
PIK3CG P48736 1/20 0.32
KCNH2 Q12809 1/20 0.32
BRDT Q58F21 1/20 0.32
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18156883 0.97 ALOX5 (0.43) ALOX5PARP14GPR3MAPTRAB9A
SCHEMBL18732424 0.90 ALOX5 (0.38) ALOX5PARP14GPR3MAPTRAB9A
SCHEMBL18732421 0.89 PDK2 (0.37) ALOX5PARP14GPR3MAPTPRKDC
SCHEMBL18732425 0.89 PDK2 (0.39) ALOX5PARP14GPR3MAPTRAB9A
SCHEMBL18374832 0.88 PARP14 (0.45) ALOX5PARP14GPR3MAPTRAB9A
SCHEMBL18732203 0.87 ALOX5 (0.35) ALOX5PARP14GPR3PRKDC
SCHEMBL22930696 0.87 PRKDC (0.38) ALOX5PARP14GPR3MAPTRAB9A
SCHEMBL15593062 0.86 PARP14 (0.48) ALOX5PARP14GPR3MAPTRAB9A
SCHEMBL22105082 0.85 ALOX5 (0.46) ALOX5PARP14GPR3MAPTRAB9A
SCHEMBL438622 0.85 PARP14 (0.50) ALOX5PARP14GPR3MAPTRAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same LG CHEM, LTD. 2021-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10910567-B2 Double spiro-type compound and organic light emitting diode comprising same NR2E3, ALDH1A2, CRY1 ALOX5 2498/4885PARP14 3074/4885GPR3 2399/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.