Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PRKDC | P78527 | 7/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.33 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | BRDT | Q58F21 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22930729 | 0.97 | ALOX5 (0.41) | ALOX5GPR3PARP14MAPTRAB9A | |
| SCHEMBL15593062 | 0.89 | PARP14 (0.48) | ALOX5GPR3PARP14MAPTRAB9A | |
| SCHEMBL20224561 | 0.88 | ALOX5 (0.39) | ALOX5GPR3PARP14MAPTRAB9A | |
| SCHEMBL19760329 | 0.88 | PDK2 (0.38) | ALOX5GPR3PARP14MAPTPRKDC | |
| SCHEMBL20224559 | 0.88 | ALOX5 (0.39) | ALOX5GPR3PARP14MAPTRAB9A | |
| SCHEMBL15434191 | 0.87 | PARP14 (0.38) | ALOX5GPR3PARP14MAPTPRKDC | |
| SCHEMBL18732424 | 0.87 | ALOX5 (0.38) | ALOX5GPR3PARP14MAPTRAB9A | |
| SCHEMBL17299574 | 0.87 | ALOX5 (0.39) | ALOX5GPR3PARP14MAPTRAB9A | |
| SCHEMBL18732421 | 0.86 | PDK2 (0.37) | ALOX5GPR3PARP14MAPTPRKDC | |
| SCHEMBL18732425 | 0.86 | PDK2 (0.39) | ALOX5GPR3PARP14MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3238286-B1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2024-01-17 | — | — | EP | disclosed |
| US-10224492-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2019-03-05 | — | — | US | disclosed |
| US-20180006245-A1 | MATERIALS FOR ELECTRONIC DEVICES | MERCK PATENT GMBH (DE) | 2018-01-04 | — | — | US | disclosed |
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | MERCK PATENT GMBH (DE) | 2016-10-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160308147-A1 | HETEROCYCLIC SPIRO COMPOUNDS | NES, KCNC1, HCN4 | ALOX5 3721/4885GPR3 2622/4885PARP14 1220/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.