SCHEMBL15434693

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7327831	0.82	PAOX (0.43)	PAOXTP53KDM4EALDH1A1SIGMAR1
	SCHEMBL8842340	0.82	PAOX (0.43)	PAOXTP53KDM4EALDH1A1HDAC6
	SCHEMBL15434606	0.81	SMN1; SMN2 (0.54)	KDM4EALDH1A1SMN1; SMN2
	SCHEMBL19407922	0.78	L3MBTL1 (0.40)	PAOXTP53KDM4EALDH1A1HDAC6
	SCHEMBL15434627	0.75	CYP4F2 (0.47)	PAOXKDM4EALDH1A1SIGMAR1TDP1
	SCHEMBL24769802	0.74	ALDH1A1 (0.40)	PAOXTP53ALDH1A1SIGMAR1CHRM2
	SCHEMBL18736050	0.74	ALDH1A1 (0.40)	PAOXTP53ALDH1A1TSHRMAPT
	SCHEMBL16940032	0.74	ALDH1A1 (0.40)	PAOXTP53ALDH1A1SIGMAR1SMN1; SMN2
	SCHEMBL16940036	0.73	ALDH1A1 (0.45)	PAOXTP53KDM4EALDH1A1
	SCHEMBL15434662	0.73	ALDH1A1 (0.45)	PAOXTP53KDM4EALDH1A1SIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.