Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | CCR6 | P51684 | 2/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | CXCR5 | P32302 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15435371 | 0.88 | FAAH (0.33) | ALDH1A1NPC1RAB9A | |
| SCHEMBL732169 | 0.79 | ALDH1A1 (0.41) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL12712806 | 0.77 | MAPT (0.33) | MAPTALDH1A1LMNACYP1A2CYP2C9 | |
| SCHEMBL31236475 | 0.65 | MEN1 (0.51) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL7598259 | 0.65 | MEN1 (0.51) | ALDH1A1NPC1RAB9AMEN1KMT2A | |
| SCHEMBL734321 | 0.64 | FAAH (0.43) | MAPTALDH1A1HPGDGAANPC1 | |
| SCHEMBL15435483 | 0.63 | EPHX2 (0.34) | MAPTALDH1A1HPGDMEN1KMT2A | |
| Lithium Ion SCHEMBL9838485 | 0.62 | EPHX2 (0.34) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL8445464 | 0.62 | EPHX2 (0.34) | MAPTALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL733052 | 0.61 | ENPP2 (0.41) | MAPTALDH1A1HPGDKDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1594855-B1 | SIGNALLING COMPOUNDS FOR USE IN METHODS OF DETECTING HYDROGEN PEROXIDE | LUMIGEN INC (US) | 2014-01-22 | — | — | EP | disclosed |