SCHEMBL15435593

SCHEMBL15435593

Cc1ccc2c(c1)C(N)c1cc(C)ccc1-2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 0.39
ALOX15 P16050 2/20 0.39
TP53 P04637 1/20 0.39
CYP3A4 P08684 1/20 0.39
THRB P10828 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
MAOA P21397 1/20 0.38
MAOB P27338 1/20 0.38
CYP1A2 P05177 3/20 0.38
CYP2A6 P11509 2/20 0.38
ALDH1A1 P00352 3/20 0.37
ELANE P08246 1/20 0.37
CHRNB2 P17787 1/20 0.36
CHRNA4 P43681 1/20 0.36
HTR7 P34969 2/20 0.35
HTR2B P41595 2/20 0.35
HSD17B10 Q99714 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 1/20 0.34
CA4 P22748 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16230462 0.89 HTR7 (0.47) TDP1CYP1A2CYP2A6ALDH1A1ELANE
SCHEMBL13825602 0.77 MAOA (0.39) TDP1ALOX15TP53CYP3A4THRB
SCHEMBL27980189 0.76 ELANE (0.44) SMN1; SMN2ALDH1A1ELANEHTR7HTR2B
SCHEMBL15435550 0.75 CYP1A2 (0.33) CYP1A2CYP2A6ALDH1A1ELANEHSD17B10
SCHEMBL23222447 0.75 DYRK1A (0.39) TDP1ALOX15TP53CYP3A4THRB
SCHEMBL29174122 0.75 MAOB (0.38) TDP1ALOX15TP53CYP3A4THRB
SCHEMBL8752734 0.75 DYRK1A (0.56) TDP1TP53MAOAMAOBCYP1A2
SCHEMBL5684539 0.75 TDP1 (0.40) TDP1ALOX15TP53CYP3A4THRB
SCHEMBL12378277 0.75 MAOA (0.38) TDP1ALOX15TP53CYP3A4THRB
Hydrochloric Acid SCHEMBL5985822 0.73 TDP1 (0.38) TDP1ALOX15TP53CYP3A4THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687304-A1 METAL COMPLEX COMPOSITIONS AND MIXTURE THEREOF Sumitomo Chemical Company Limited (JP) 2014-01-22 EP disclosed