SCHEMBL15435550

SCHEMBL15435550

Cc1ccc2c(c1)C(N)c1cc(C)c3ccccc3c1-2

nearest known ligand 0.33

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 3/20 0.33
CYP2A6 P11509 1/20 0.33
ALDH1A1 P00352 1/20 0.33
HPGD P15428 1/20 0.33
HSD17B10 Q99714 1/20 0.33
KDM4E B2RXH2 1/20 0.33
NPC1 O15118 1/20 0.33
KMT2A Q03164 1/20 0.33
ELANE P08246 1/20 0.33
GRM2 Q14416 1/20 0.32
GAA P10253 1/20 0.31
KIF11 P52732 1/20 0.31
NTRK1 P04629 1/20 0.31
BACE1 P56817 1/20 0.30
PDK2 Q15119 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10111189 0.79 GPR3 (0.40) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL15435551 0.79 KMT2A (0.33) CYP1A2ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL10111002 0.77 GRM2 (0.36) CYP1A2ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL10111193 0.76 KDM1A (0.34) CYP1A2ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL15435593 0.75 TDP1 (0.39) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL16230462 0.74 HTR7 (0.47) CYP1A2CYP2A6ALDH1A1HPGDHSD17B10
SCHEMBL10111005 0.74 ALDH1A1 (0.37) CYP1A2ALDH1A1HPGDHSD17B10KDM4E
SCHEMBL10126527 0.71 BCHE (0.36) CYP1A2
SCHEMBL22990005 0.65 CYP1A2 (0.35) CYP1A2CYP2A6ELANEGRM2KIF11
SCHEMBL27980189 0.64 ELANE (0.44) ALDH1A1KMT2AELANE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687304-A1 METAL COMPLEX COMPOSITIONS AND MIXTURE THEREOF Sumitomo Chemical Company Limited (JP) 2014-01-22 EP disclosed