Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | DRD1 | P21728 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11661389 | 0.76 | TP53 (0.36) | TSHRALDH1A1TP53GLACHRM2 | |
| SCHEMBL6289830 | 0.72 | TSHR (0.36) | TSHRALDH1A1GLAOPRM1AOC3 | |
| SCHEMBL28246803 | 0.70 | TSHR (0.35) | TSHRALDH1A1GLAOPRM1AOC3 | |
| Biphenyl SCHEMBL27328558 | 0.67 | ALDH1A1 (0.45) | ALDH1A1TP53SLC6A4 | |
| SCHEMBL28813774 | 0.65 | TP53 (0.39) | TSHRALDH1A1TP53GLALMNA | |
| Propane SCHEMBL1423596 | 0.64 | TP53 (0.43) | TSHRALDH1A1TP53GLALMNA | |
| Propane SCHEMBL372201 | 0.64 | TP53 (0.43) | TSHRALDH1A1TP53GLALMNA | |
| Biphenyl SCHEMBL5689469 | 0.64 | ALDH1A1 (0.47) | TSHRALDH1A1TP53GLASLC6A4 | |
| SCHEMBL28846628 | 0.64 | TSHR (0.46) | TSHRALDH1A1TP53GLACHRM2 | |
| SCHEMBL5351474 | 0.64 | TP53 (0.38) | TSHRTP53GLALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328905-B1 | ETHYLENE TETRAMERIZATION CATALYSTS COMPRISING P-N-P LIGANDS | NOVA CHEM INT SA (CH) | 2014-01-22 | — | — | EP | disclosed |