Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 10/20 | 0.55 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.49 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | PPARG | P37231 | 1/20 | 0.49 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10367487 | 1.00 | TDP1 (0.56) | TDP1FFAR1FFAR4LMNAL3MBTL1 | |
| SCHEMBL28669960 | 0.91 | MGLL (0.55) | TDP1FFAR1FFAR4LMNAALDH1A1 | |
| SCHEMBL17063071 | 0.86 | TDP1 (0.50) | TDP1FFAR1FFAR4LMNAALDH1A1 | |
| SCHEMBL32685172 | 0.85 | MGLL (0.52) | TDP1FFAR1LMNAL3MBTL1ALDH1A1 | |
| SCHEMBL9628741 | 0.84 | TDP1 (0.59) | TDP1LMNAALDH1A1GAAPKM | |
| SCHEMBL2733663 | 0.84 | TDP1 (0.59) | TDP1LMNAALDH1A1GAAPKM | |
| SCHEMBL9628757 | 0.84 | TDP1 (0.59) | TDP1LMNAALDH1A1GAAPKM | |
| SCHEMBL1041018 | 0.84 | PKM (0.50) | TDP1LMNAALDH1A1GAAPKM | |
| SCHEMBL8437625 | 0.84 | PKM (0.50) | TDP1LMNAALDH1A1GAAPKM | |
| SCHEMBL13654852 | 0.84 | PKM (0.50) | TDP1LMNAALDH1A1GAAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687521-B1 | \"Process for the enantioselective synthesis of landiolol\ | PROCOS SPA (IT) | 2015-01-07 | — | — | EP | disclosed |
| EP-2687521-A1 | \"Process for the enantioselective synthesis of landiolol\ | Procos S.p.A. (IT) | 2014-01-22 | — | — | EP | disclosed |