Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | REN | P00797 | 17/20 | 0.38 |
| ▸ | ACACB | O00763 | 2/20 | 0.36 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.36 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12524633 | 0.92 | REN (0.39) | RENACACBROCK2ROCK1 | |
| SCHEMBL15417928 | 0.86 | HSP90AA1 (0.39) | RENACACBROCK2ROCK1 | |
| SCHEMBL12524635 | 0.85 | ROCK2 (0.39) | RENACACBROCK2ROCK1 | |
| SCHEMBL15435832 | 0.85 | PARP15 (0.42) | RENACACBROCK2ROCK1 | |
| SCHEMBL17013214 | 0.78 | REN (0.37) | RENACACB | |
| SCHEMBL12524621 | 0.78 | KDM1A (0.45) | REN | |
| SCHEMBL12524624 | 0.78 | REN (0.45) | REN | |
| SCHEMBL17013215 | 0.77 | KDM4E (0.37) | REN | |
| SCHEMBL12525841 | 0.77 | DUT (0.40) | RENACACB | |
| SCHEMBL15435676 | 0.76 | REN (0.37) | RENACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687518-A1 | NITROGEN-CONTAINING SATURATED HETEROCYCLIC COMPOUND | Mitsubishi Tanabe Pharma Corporation (JP) | 2014-01-22 | — | — | EP | disclosed |