SCHEMBL15436115

SCHEMBL15436115

c1ccc2c(-n3c4ccccc4c4cc(-c5ccc6c(c5)c5ccccc5n6-c5ccc(-n6c7ccccc7c7ccccc76)cc5)ccc43)cccc2c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
POLB P06746 1/20 0.38
ALDH1A1 P00352 2/20 0.37
CNR1 P21554 1/20 0.37
CNR2 P34972 1/20 0.37
TDP1 Q9NUW8 1/20 0.36
GSK3A P49840 1/20 0.36
GSK3B P49841 1/20 0.36
HDAC4 P56524 1/20 0.36
PTGS1 P23219 1/20 0.34
PTGS2 P35354 1/20 0.34
GSR P00390 1/20 0.34
PTGER4 P35408 1/20 0.34
NPC1 O15118 1/20 0.34
MAPK1 P28482 1/20 0.34
HTR3E A5X5Y0 1/20 0.34
HTR3B O95264 1/20 0.34
CYP1A2 P05177 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18623557 0.98 KDM4E (0.44) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL16206337 0.96 KDM4E (0.46) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL21531894 0.96 KDM4E (0.46) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL11981049 0.96 L3MBTL1 (0.50) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL16206360 0.96 KDM4E (0.46) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL9888811 0.95 L3MBTL1 (0.53) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL21923146 0.95 KDM4E (0.41) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL14900795 0.95 L3MBTL1 (0.53) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL22173021 0.94 KDM4E (0.45) KDM4EATML3MBTL1POLBALDH1A1
SCHEMBL22876496 0.94 KDM4E (0.45) KDM4EATML3MBTL1POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element IDEMITSU KOSAN CO., LTD. (JP) 2020-07-07 US disclosed
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2019-01-17 US disclosed
EP-2688120-B1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT TORAY INDUSTRIES (JP) 2017-08-23 EP disclosed
US-9564595-B2 Bis-carbazole derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-02-07 US disclosed
US-9564595-B2 Bis-carbazole derivative and organic electroluminescent element using same IDEMITSU KOSAN CO., LTD. (JP) 2017-02-07 US disclosed
US-9537107-B2 Light emitting device material and light emitting device TORAY INDUSTRIES, INC. (JP) 2017-01-03 US disclosed
US-20140306207-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT IDEMITSU KOSAN CO., LTD. (JP) 2014-10-16 US disclosed
EP-2688120-A1 LIGHT-EMITTING ELEMENT MATERIAL AND LIGHT-EMITTING ELEMENT Toray Industries, Inc. (JP) 2014-01-22 EP disclosed
US-20140008633-A1 BIS-CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MITSUI CHEMICALS, INC (JP) 2014-01-09 US disclosed
US-20140008633-A1 BIS-CARBAZOLE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT ELEMENT USING SAME MITSUI CHEMICALS, INC (JP) 2014-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190019972-A1 ORGANIC ELECTROLUMINESCENCE ELEMENT, AND MATERIAL FOR ORGANIC ELECTROLUMINESCENCE ELEMENT LEF1, L1CAM, AGO2 KDM4E 3248/4885ATM 2324/4885L3MBTL1 1678/4885
US-10707434-B2 Organic electroluminescence element, and material for organic electroluminescence element LEF1, L1CAM, AGO2 KDM4E 3248/4885ATM 2324/4885L3MBTL1 1678/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.