SCHEMBL15436209

SCHEMBL15436209

O=c1oc(-c2ccc(O)cc2)nc2ccc(O)cc12

nearest known ligand 0.75

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.75
MAPT P10636 4/20 0.75
MEN1 O00255 2/20 0.75
KMT2A Q03164 2/20 0.75
TDP1 Q9NUW8 1/20 0.75
HSD17B10 Q99714 1/20 0.64
ESR2 Q92731 10/20 0.61
ESR1 P03372 9/20 0.61
ELANE P08246 1/20 0.54
NPC1 O15118 4/20 0.51
RXFP1 Q9HBX9 1/20 0.51
TP53 P04637 1/20 0.48
KDM4E B2RXH2 1/20 0.48
ALDH1A1 P00352 1/20 0.48
LMNA P02545 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
HDAC6 Q9UBN7 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2539367 0.98 MAPT (0.77) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL6565915 0.91 MAPT (0.68) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL15436301 0.81 MAPT (0.67) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL17574394 0.81 ELANE (0.69) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL12352144 0.81 MEN1 (0.56) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL6565079 0.79 MAPT (0.54) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL6565665 0.79 TP53 (0.70) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL2328301 0.79 ALDH1A1 (0.63) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL6565178 0.79 ELANE (0.56) RAB9AMAPTMEN1KMT2ATDP1
SCHEMBL2333007 0.79 RAB9A (0.69) RAB9AMAPTMEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2687517-B1 POLYMERIZABLE COMPOUND, POLYMERIZABLE LIQUID CRYSTALLINE COMPOSITION, MACROMOLECULAR COMPOUND AND FILM FUJIFILM CORP (JP) 2015-12-09 EP disclosed
US-8784684-B2 Polymerizable compound, polymerizable liquid crystalline composition, macromolecular compound and film FUJIFILM CORPORATION (JP) 2014-07-22 US disclosed
US-8784684-B2 Polymerizable compound, polymerizable liquid crystalline composition, macromolecular compound and film FUJIFILM CORPORATION (JP) 2014-07-22 US disclosed
EP-2687517-A1 POLYMERIZABLE COMPOUND, POLYMERIZABLE LIQUID CRYSTAL COMPOSITION, POLYMERIC COMPOUND, AND FILM FUJIFILM Corporation (JP) 2014-01-22 EP disclosed