Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | MGLL | Q99685 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.36 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | HTR7 | P34969 | 1/20 | 0.35 |
| ▸ | TOP1 | P11387 | 2/20 | 0.35 |
| ▸ | REN | P00797 | 3/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21454383 | 0.91 | L3MBTL1 (0.45) | GRM5ALDH1A1HTTATMTSHR | |
| SCHEMBL20998100 | 0.90 | ALDH1A1 (0.37) | GRM5ALDH1A1ATMLIMK1TSHR | |
| SCHEMBL15617059 | 0.86 | ALDH1A1 (0.34) | GRM5ALDH1A1CYP11B1CYP11B2LIMK1 | |
| SCHEMBL21453866 | 0.84 | L3MBTL1 (0.41) | GRM5ALDH1A1HTTATMTSHR | |
| SCHEMBL17348983 | 0.84 | ATM (0.42) | GRM5ALDH1A1FAAHHSP90AA1PKM | |
| SCHEMBL19037145 | 0.84 | GRM5 (0.36) | GRM5ALDH1A1FAAHHSP90AA1PKM | |
| SCHEMBL15335487 | 0.84 | LIMK1 (0.32) | GRM5ALDH1A1LIMK1TSHRCYP2C19 | |
| SCHEMBL9968180 | 0.84 | L3MBTL1 (0.43) | GRM5ALDH1A1HSP90AA1HTTATM | |
| SCHEMBL17348996 | 0.83 | L3MBTL1 (0.45) | GRM5ALDH1A1HSP90AA1HTTATM | |
| SCHEMBL17349041 | 0.83 | DCTPP1 (0.37) | GRM5ALDH1A1FAAHHSP90AA1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| US-9543526-B2 | Nitrogen-containing aromatic compounds and organic electroluminescent device | NIPPON STEEL & SUMIKIN CHEMICAL CO., LTD. (JP) | 2017-01-10 | — | — | US | disclosed |
| EP-2687530-A1 | NITROGEN-CONTAINING AROMATIC COMPOUNDS AND ORGANIC ELECTROLUMINESCENT ELEMENTS | Nippon Steel & Sumikin Chemical Co., Ltd. (JP) | 2014-01-22 | — | — | EP | disclosed |