Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR4 | Q13639 | 1/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15436734 | 0.96 | HTR4 (0.32) | HTR4JAK1 | |
| SCHEMBL15436729 | 0.95 | HTR4 (0.36) | HTR4JAK1 | |
| SCHEMBL14943870 | 0.90 | HTR4 (0.36) | HTR4JAK1 | |
| SCHEMBL13238646 | 0.82 | P2RX7 (0.41) | HTR4P2RX7JAK1 | |
| SCHEMBL15436478 | 0.80 | METTL3 (0.32) | — | |
| SCHEMBL14943864 | 0.80 | HTR4 (0.32) | HTR4 | |
| SCHEMBL13238648 | 0.78 | P2RX7 (0.37) | HTR4P2RX7JAK1 | |
| SCHEMBL14898663 | 0.77 | P2RX7 (0.39) | P2RX7 | |
| SCHEMBL3031736 | 0.77 | HRH2 (0.36) | HTR4JAK1 | |
| SCHEMBL3031734 | 0.77 | HRH2 (0.36) | HTR4JAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2096923-B1 | HETEROARYL AMIDE DERIVATIVES | LUNDBECK & CO AS H (DK) | 2014-01-22 | — | — | EP | disclosed |