Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 16/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3610683 | 0.87 | FAAH (0.67) | FAAH | |
| SCHEMBL22684350 | 0.87 | HRH3 (0.46) | FAAHALDH1A1LMNAKDM4E | |
| SCHEMBL20570688 | 0.83 | FAAH (0.55) | FAAHALDH1A1LMNAHPGDHTT | |
| SCHEMBL4185470 | 0.81 | VEGFA (0.47) | FAAHALDH1A1LMNA | |
| SCHEMBL6334625 | 0.80 | FAAH (0.53) | FAAHALDH1A1LMNAHTTKDM4E | |
| SCHEMBL2778173 | 0.80 | FAAH (0.53) | FAAHALDH1A1LMNAKDM4E | |
| SCHEMBL20570037 | 0.80 | FAAH (0.50) | FAAHALDH1A1KDM4E | |
| SCHEMBL27591252 | 0.79 | HRH3 (0.42) | FAAHALDH1A1LMNAKDM4E | |
| SCHEMBL3617972 | 0.79 | ALDH1A1 (0.68) | FAAHALDH1A1LMNAHPGDHTT | |
| SCHEMBL5031225 | 0.79 | LMNA (0.59) | ALDH1A1LMNAHPGDHTTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687516-A1 | Inhibitors of C-FMS Kinase | Janssen Pharmaceutica N.V. (BE) | 2014-01-22 | — | — | EP | disclosed |