Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSF1R | P07333 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 5/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CFTR | P13569 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | MLYCD | O95822 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15436669 | 0.83 | CSF1R (0.41) | CSF1RNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL15436762 | 0.81 | CSF1R (0.41) | CSF1RNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL15436508 | 0.77 | KMT2A (0.46) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL15436573 | 0.77 | POLB (0.45) | NPC1RAB9ASMN1; SMN2KMT2AMEN1 | |
| SCHEMBL14383434 | 0.76 | CSF1R (0.74) | CSF1R | |
| SCHEMBL15436835 | 0.75 | CSF1R (0.43) | CSF1RNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL15436577 | 0.75 | CSF1R (0.47) | CSF1RSMN1; SMN2MAPT | |
| SCHEMBL15436505 | 0.75 | CSF1R (0.39) | CSF1RKMT2AALDH1A1GAA | |
| SCHEMBL15436790 | 0.73 | ALDH1A1 (0.48) | CSF1RNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL15436493 | 0.71 | CSF1R (0.40) | CSF1RNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687516-A1 | Inhibitors of C-FMS Kinase | Janssen Pharmaceutica N.V. (BE) | 2014-01-22 | — | — | EP | disclosed |