Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.42 |
| ▸ | CSF1R | P07333 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15418562 | 0.83 | LMNA (0.49) | LMNA | |
| SCHEMBL5651332 | 0.81 | CSF1R (0.49) | HDAC1HDAC2HDAC3CSF1RKIT | |
| Hydrochloric Acid SCHEMBL5654851 | 0.81 | CSF1R (0.49) | HDAC1HDAC2HDAC3CSF1RKIT | |
| SCHEMBL22684350 | 0.78 | HRH3 (0.46) | FAAHLMNATSHRALDH1A1HRH3 | |
| SCHEMBL15436733 | 0.75 | FAAH (0.53) | FAAHLMNAALDH1A1 | |
| SCHEMBL15418560 | 0.74 | CHEK1 (0.45) | CSF1RKITGRM2LMNAHRH3 | |
| SCHEMBL4179494 | 0.73 | CSF1R (0.52) | HDAC1HDAC2HDAC3CSF1RKIT | |
| SCHEMBL6334625 | 0.72 | FAAH (0.53) | FAAHLMNAALDH1A1HRH3SMN1; SMN2 | |
| SCHEMBL2778173 | 0.72 | FAAH (0.53) | FAAHLMNAALDH1A1NPSR1KMT2A | |
| SCHEMBL3082188 | 0.72 | CSF1R (0.45) | HDAC1HDAC2HDAC3CSF1RKIT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2687516-A1 | Inhibitors of C-FMS Kinase | Janssen Pharmaceutica N.V. (BE) | 2014-01-22 | — | — | EP | disclosed |