SCHEMBL154384

SCHEMBL154384

NC(=O)CCc1ccc(O)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA2 P00918 3/20 0.61
ESR1 P03372 2/20 0.56
ESR2 Q92731 1/20 0.56
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 3/20 0.54
CYP2C19 P33261 2/20 0.54
HTR1A P08908 1/20 0.54
ADRA2A P08913 1/20 0.54
SLC6A2 P23975 1/20 0.54
HTR3A P46098 1/20 0.54
BACE1 P56817 1/20 0.54
TAAR1 Q96RJ0 1/20 0.54
L3MBTL1 Q9Y468 1/20 0.54
KMT2A Q03164 2/20 0.53
TDP1 Q9NUW8 2/20 0.53
CYP19A1 P11511 2/20 0.53
LMNA P02545 2/20 0.53
HDAC2 Q92769 1/20 0.53
HDAC8 Q9BY41 1/20 0.53
MEN1 O00255 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20399733 0.94 HDAC2 (0.62) CA2ESR1ESR2ALDH1A1KDM4E
Butane SCHEMBL10453910 0.92 CA2 (0.53) CA2ESR1ESR2ALDH1A1KDM4E
SCHEMBL934532 0.89 CA2 (0.59) CA2ESR1ESR2ALDH1A1KDM4E
SCHEMBL4938894 0.87 ACHE (0.57) CA2ESR1ESR2ALDH1A1KDM4E
Hydroxyphenyl Propionic Acid SCHEMBL27946436 0.86 FFAR1 (0.55) CA2ESR1ESR2MAPTCAMK2A
SCHEMBL5724132 0.85 ACHE (0.60) CA2ESR1ESR2ALDH1A1KDM4E
Phenol SCHEMBL28125145 0.85 KEAP1 (0.57) ALDH1A1TDP1CYP19A1HDAC2HDAC8
SCHEMBL31390626 0.85 ACHE (0.60) CA2ESR1ESR2ALDH1A1KDM4E
Butylamine SCHEMBL27609975 0.84 ESR1 (0.51) CA2ESR1ESR2ALDH1A1KDM4E
SCHEMBL4667379 0.82 CAPN1 (0.52) ALDH1A1LMNACAPN1ABATPRMT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4145 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3990534-B1 MIXED ESTER TEREPHTHALATE COMPOSITIONS USEFUL AS PLASTICIZERS EASTMAN CHEM CO (US) 2025-12-10 EP claimed
CN-119684260-A Ferritin ligand, ferritin degradation agent, pharmaceutical preparation and application 贵州大学 2025-03-25 CN claimed
US-12060334-B2 3-substituted phenazine derivatives as antimicrobial agents UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED (US) 2024-08-13 US claimed
EP-3715346-B1 THIAZOLYL-CONTAINING COMPOUNDS FOR TREATING PROLIFERATIVE DISEASES DANA FARBER CANCER INST INC (US) 2024-01-03 EP claimed
EP-4277636-A1 MODIFIED OLIGONUCLEOTIDES Alnylam Pharmaceuticals, Inc. (US) 2023-11-22 EP claimed
EP-3606528-B1 TRICYCLIC COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 (GSK3) INHIBITORS AND USES THEREOF BROAD INST INC (US) 2023-10-18 EP claimed
WO-2022155418-A9 MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2023-03-09 WO claimed
EP-3291676-B1 MITRAGYNINE ANALOGS AND USES THEREOF MEMORIAL SLOAN KETTERING CANCER CENTER (US) 2022-08-17 EP claimed
WO-2022155418-A1 MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2022-07-21 WO claimed
US-11241435-B2 Uses of salt-inducible kinase (SIK) inhibitors for treating osteoporosis THE GENERAL HOSPITAL CORPORATION (US) 2022-02-08 US claimed
EP-1153024-B1 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS NOVARTIS AG (CH) 2004-04-28 EP claimed
EP-0874846-B1 PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION NOVARTIS AG (CH) 2003-04-02 EP claimed
JP-2002537300-A 2002-11-05 JP claimed
US-20020016329-A1 2-Amino-6-anilino-purines and their use as medicaments NOVARTIS AG (CH) 2002-02-07 US claimed
EP-1153024-A1 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS Novartis AG (CH) 2001-11-14 EP claimed
WO-2000049018-A1 2-AMINO-6-ANILINO-PURINES AND THEIR USE AS MEDICAMENTS NOVARTIS AG (CH) 2000-08-24 WO claimed
EP-0874846-A1 PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION Novartis AG (CH) 1998-11-04 EP claimed
WO-1997016452-A1 PURINE DERIVATIVES AND PROCESSES FOR THEIR PREPARATION NOVARTIS AG (CH) 1997-05-09 WO claimed
EP-0218768-A2 Compositions containing antimicrobial agents in combination with stabilizers MORTON THIOKOL, INC. (US) 1987-04-22 EP claimed
EP-0003809-B1 COPOLYETHERESTER COMPOSITIONS STABILIZED AGAINST OXIDATIVE DEGRADATION AND PROCESS FOR THEIR MANUFACTURE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1983-04-13 EP claimed