Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFTR | P13569 | 1/20 | 0.34 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439948 | 0.97 | CFTR (0.34) | CFTRGOPCMEN1HTTKMT2A | |
| SCHEMBL15440392 | 0.84 | MEN1 (0.38) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15439812 | 0.82 | ALDH1A1 (0.47) | MEN1KMT2AGAAMAPTALDH1A1 | |
| SCHEMBL15439378 | 0.78 | CYP2A6 (0.33) | — | |
| SCHEMBL15440323 | 0.75 | CFTR (0.33) | CFTRGOPCMEN1HTTKMT2A | |
| SCHEMBL15439867 | 0.74 | NPC1 (0.36) | MEN1HTTKMT2AGAAALDH1A1 | |
| SCHEMBL15439914 | 0.73 | ALDH1A1 (0.32) | MEN1HTTKMT2AMAPTALDH1A1 | |
| SCHEMBL15439396 | 0.72 | ALDH1A1 (0.33) | MEN1HTTKMT2AGAAMAPT | |
| SCHEMBL15440407 | 0.72 | MAPT (0.34) | MEN1HTTKMT2AGAAMAPT | |
| SCHEMBL15439866 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |