Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | MIF | P14174 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.32 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440099 | 0.73 | ALDH1A1 (0.30) | ALDH1A1HTTHSP90AA1HPGDXBP1 | |
| SCHEMBL15439661 | 0.72 | ALDH1A1 (0.33) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL15438847 | 0.72 | CFTR (0.34) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL15439948 | 0.72 | CFTR (0.34) | ALDH1A1MEN1KMT2AHTTALOX15 | |
| SCHEMBL15439662 | 0.71 | MIF (0.40) | ALDH1A1BLMMIF | |
| SCHEMBL15440407 | 0.69 | MAPT (0.34) | ALDH1A1MEN1KMT2AGAAMAPT | |
| SCHEMBL15440541 | 0.69 | DEPTOR (0.37) | ALDH1A1MEN1KMT2AMAPT | |
| SCHEMBL15439378 | 0.68 | CYP2A6 (0.33) | — | |
| SCHEMBL15440392 | 0.68 | MEN1 (0.38) | ALDH1A1MEN1KMT2AKDM4EGAA | |
| SCHEMBL15439979 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |