Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
| ▸ | CES1 | P23141 | 1/20 | 0.42 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | CTBP2 | P56545 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439258 | 1.00 | CES2 (0.42) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL15438708 | 0.86 | NPC1 (0.46) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL15438710 | 0.86 | NPC1 (0.46) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL14799495 | 0.85 | ALDH1A1 (0.40) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL14799493 | 0.85 | ALDH1A1 (0.40) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL15440177 | 0.84 | GAA (0.40) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL15439815 | 0.84 | ALDH1A1 (0.40) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL15440179 | 0.84 | GAA (0.40) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL15439803 | 0.84 | G6PC1 (0.53) | CES2CES1AKR1B1NPC1RAB9A | |
| SCHEMBL15439802 | 0.84 | G6PC1 (0.53) | CES2CES1AKR1B1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |