Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 2/20 | 0.53 |
| ▸ | CES2 | O00748 | 1/20 | 0.45 |
| ▸ | CES1 | P23141 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439263 | 1.00 | G6PC1 (0.53) | G6PC1CES2CES1NPC1RAB9A | |
| SCHEMBL15440322 | 0.87 | G6PC1 (0.56) | G6PC1CES2CES1NPC1RAB9A | |
| SCHEMBL15440325 | 0.87 | G6PC1 (0.56) | G6PC1CES2CES1NPC1RAB9A | |
| SCHEMBL15439176 | 0.86 | NPC1 (0.46) | G6PC1CES2CES1NPC1RAB9A | |
| SCHEMBL15439177 | 0.86 | NPC1 (0.46) | G6PC1CES2CES1NPC1RAB9A | |
| SCHEMBL15438901 | 0.84 | CES2 (0.41) | G6PC1CES2CES1NPC1RAB9A | |
| SCHEMBL15438899 | 0.84 | CES2 (0.41) | G6PC1CES2CES1NPC1RAB9A | |
| SCHEMBL14799574 | 0.83 | G6PC1 (0.54) | G6PC1NPC1RAB9ACA12CA9 | |
| SCHEMBL14799576 | 0.83 | G6PC1 (0.54) | G6PC1NPC1RAB9ACA12CA9 | |
| SCHEMBL15440288 | 0.82 | CES2 (0.41) | G6PC1CES2CES1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |