Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.36 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15438901 | 1.00 | CES2 (0.41) | CES2CES1RAB9ANPC1LMNA | |
| SCHEMBL15439788 | 0.88 | LMNA (0.41) | CES2CES1RAB9ANPC1LMNA | |
| SCHEMBL15439786 | 0.88 | LMNA (0.41) | CES2CES1RAB9ANPC1LMNA | |
| SCHEMBL14800046 | 0.84 | G6PC1 (0.40) | RAB9ANPC1LMNAG6PC1KMT2A | |
| SCHEMBL14800048 | 0.84 | G6PC1 (0.40) | RAB9ANPC1LMNAG6PC1KMT2A | |
| SCHEMBL15439263 | 0.84 | G6PC1 (0.53) | CES2CES1RAB9ANPC1LMNA | |
| SCHEMBL15439262 | 0.84 | G6PC1 (0.53) | CES2CES1RAB9ANPC1LMNA | |
| SCHEMBL15440188 | 0.83 | G6PC1 (0.44) | RAB9ANPC1LMNAG6PC1KMT2A | |
| SCHEMBL15440191 | 0.83 | G6PC1 (0.44) | RAB9ANPC1LMNAG6PC1KMT2A | |
| SCHEMBL14799829 | 0.83 | G6PC1 (0.49) | RAB9ANPC1LMNAG6PC1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |