Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | G6PC1 | P35575 | 11/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.35 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439017 | 0.82 | TSHR (0.44) | MAOAMAOBCA12CA9ALDH1A1 | |
| SCHEMBL15439742 | 0.78 | ALDH1A1 (0.36) | G6PC1MAOAMAOBCA12CA9 | |
| SCHEMBL15440189 | 0.78 | TSHR (0.36) | G6PC1MAOAMAOBCA12CA9 | |
| SCHEMBL15439386 | 0.71 | G6PC1 (0.40) | G6PC1MAOAMAOBCA12CA9 | |
| SCHEMBL15438517 | 0.69 | G6PC1 (0.43) | G6PC1CA12CA9ALDH1A1TSHR | |
| SCHEMBL15439235 | 0.69 | G6PC1 (0.46) | G6PC1CA12CA9ALDH1A1TSHR | |
| SCHEMBL15438519 | 0.69 | G6PC1 (0.43) | G6PC1CA12CA9ALDH1A1TSHR | |
| SCHEMBL3413430 | 0.69 | G6PC1 (0.52) | G6PC1CA12CA9ALDH1A1TSHR | |
| SCHEMBL14799680 | 0.68 | G6PC1 (0.53) | G6PC1CA12CA9ALDH1A1TSHR | |
| SCHEMBL15439407 | 0.67 | G6PC1 (0.59) | G6PC1CA12CA9ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |