Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | MPI | P34949 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439017 | 0.79 | TSHR (0.44) | ALDH1A1TSHRAOC3MAOBMAOA | |
| SCHEMBL15439429 | 0.78 | G6PC1 (0.42) | ALDH1A1TSHRAOC3MAOBMAOA | |
| SCHEMBL15439609 | 0.76 | TSHR (0.34) | ALDH1A1TSHRAOC3MAOBNPC1 | |
| SCHEMBL15440189 | 0.75 | TSHR (0.36) | ALDH1A1TSHRAOC3MAOBMAOA | |
| SCHEMBL15439867 | 0.74 | NPC1 (0.36) | ALDH1A1TSHRAOC3NPC1RAB9A | |
| SCHEMBL15439732 | 0.74 | ALDH1A1 (0.35) | ALDH1A1TSHRAOC3NPC1RAB9A | |
| SCHEMBL15439801 | 0.74 | NPC1 (0.36) | ALDH1A1TSHRAOC3NPC1RAB9A | |
| SCHEMBL15438962 | 0.72 | DEPTOR (0.35) | ALDH1A1TSHRAOC3NPC1RAB9A | |
| SCHEMBL15440176 | 0.72 | MAPT (0.40) | ALDH1A1TSHRAOC3RAB9ALMNA | |
| SCHEMBL15439643 | 0.71 | MAOB (0.34) | ALDH1A1TSHRAOC3MAOBNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |