Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.35 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.35 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439386 | 0.83 | G6PC1 (0.40) | TSHRALDH1A1AOC3CA12CA9 | |
| SCHEMBL15439609 | 0.80 | TSHR (0.34) | TSHRALDH1A1AOC3NPC1RAB9A | |
| SCHEMBL15440034 | 0.74 | ALDH1A1 (0.35) | TSHRALDH1A1AOC3NPC1RAB9A | |
| SCHEMBL15439017 | 0.73 | TSHR (0.44) | TSHRALDH1A1AOC3NPC1RAB9A | |
| SCHEMBL14394126 | 0.72 | TSHR (0.36) | TSHRALDH1A1AOC3NPC1RAB9A | |
| SCHEMBL15439697 | 0.70 | G6PC1 (0.42) | TSHRALDH1A1AOC3NPC1RAB9A | |
| SCHEMBL15439696 | 0.70 | G6PC1 (0.42) | TSHRALDH1A1AOC3NPC1RAB9A | |
| SCHEMBL1165535 | 0.69 | TSHR (0.56) | TSHRALDH1A1AOC3NPC1RAB9A | |
| SCHEMBL15438782 | 0.69 | TSHR (0.42) | TSHRALDH1A1AOC3NPC1RAB9A | |
| SCHEMBL15439338 | 0.69 | TSHR (0.42) | TSHRALDH1A1AOC3NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |