SCHEMBL1165535

SCHEMBL1165535

CN(Cc1ccccc1)N=O

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.56
ALDH1A1 P00352 2/20 0.56
AOC3 Q16853 1/20 0.52
NPC1 O15118 2/20 0.48
RAB9A P51151 2/20 0.48
CA12 O43570 2/20 0.48
CA9 Q16790 2/20 0.48
CARM1 Q86X55 1/20 0.45
PRMT6 Q96LA8 1/20 0.45
PRMT8 Q9NR22 1/20 0.45
KMT2A Q03164 2/20 0.44
LMNA P02545 3/20 0.44
ADRA2B P18089 1/20 0.44
ADRA2C P18825 1/20 0.44
SLC6A2 P23975 1/20 0.44
HTR2A P28223 1/20 0.44
SLC6A4 P31645 1/20 0.44
ADRA1A P35348 1/20 0.44
OPRK1 P41145 1/20 0.44
SLC6A3 Q01959 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8817588 0.78 TAAR1 (0.59) AOC3NPC1RAB9AKMT2ATAAR1
SCHEMBL15597736 0.78 PYCR1 (0.47) ALDH1A1AOC3MAOAMAOBPYCR1
SCHEMBL29049154 0.78 ALDH1A1 (0.50) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL4696748 0.78 TSHR (0.52) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL16848072 0.77 TSHR (0.56) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL3413430 0.76 G6PC1 (0.52) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL8742976 0.76 TSHR (0.54) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL29049161 0.75 APLNR (0.53) ALDH1A1AOC3KMT2ALMNAPYCR1
SCHEMBL24688902 0.74 ALDH1A1 (0.52) TSHRALDH1A1AOC3NPC1RAB9A
SCHEMBL7236391 0.74 ALDH1A1 (0.52) TSHRALDH1A1AOC3NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 161 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112674028-B Method for establishing cancer model of animal induced by cancer inducer 汉姆德(宁波)智能医疗科技有限公司 2022-06-28 CN claimed
CN-108715845-B Construction method of esophagus epithelial tissue pol beta specificity knockout mouse esophagus precancerous lesion model 郑州大学 2021-09-24 CN claimed
CN-110715999-B High-throughput screening method for 200 chemical risk substances in toy 中国检验检疫科学研究院 2021-08-20 CN claimed
CN-113117084-A Pharmaceutical preparation for avoiding or reducing production of N-nitrosamine genotoxic substances 江南大学 2021-07-16 CN claimed
CN-112674028-A Method for establishing cancer model of animal induced by cancer inducer 汉姆德(宁波)智能医疗科技有限公司 2021-04-20 CN claimed
CN-110715999-A High-throughput screening method for 200 chemical risk substances in toy 中国检验检疫科学研究院 2020-01-21 CN claimed
EP-0428342-B1 Stable thiol-ene compositions LOCTITE IRELAND LTD (IE) 1997-01-15 EP claimed
US-5358976-A Curable; stabilization by addition of a non-acidic N-nitroso compound LOCTITE (IRELAND) LIMITED (IE) 1994-10-25 US claimed
US-4053317-A N-NITROSO COMPOUND, PHOTOPOLYMERIZABLE COMPOUND TEIJIN LIMITED (JA) 1977-10-11 US claimed
JP-5140136-A None JP disclosed
EP-4652309-A2 FLOW SYNTHESIS OF AMINES BAE SYSTEMS plc (GB) 2025-11-26 EP disclosed
US-20250354188-A1 METHOD FOR SYNTHESIZING CELOSIANIN II, METHOD FOR SYNTHESIZING BETAXANTHIN, AMYLOID-ß POLYMERIZATION INHIBITOR OR THERAPEUTIC OR PROPHYLACTIC AGENT FOR ALZHEIMER'S DISEASE, AMYLOID PEPTIDE AGGREGATION INHIBITOR, AND HIV-1 PROTEASE ACTIVITY INHIBITOR Mori, Masashi (JP) 2025-11-20 US disclosed
US-20250281445-A1 Method of dietary treatment for genetic and epigenetic diseases and disorders OTT DAVID MICHAEL (US) 2025-09-11 US disclosed
CN-120384051-A Method for constructing esophageal squamous cell precancerous lesions and cancerous cell model 东南大学 2025-07-29 CN disclosed
EP-0494225-A4 HUMAN ESOPHAGEAL EPITHELIAL CELL LINES US HEALTH (US) 1993-04-28 EP disclosed
EP-0494225-A1 HUMAN ESOPHAGEAL EPITHELIAL CELL LINES THE UNITED STATES OF AMERICA as represented by the Secretary UNITED STATES DEPARTMENT OF COMMERCE (US) 1992-07-15 EP disclosed
EP-0428342-A2 Stable thiol-ene compositions LOCTITE (IRELAND) Ltd. (IE) 1991-05-22 EP disclosed
WO-1991005062-A1 HUMAN ESOPHAGEAL EPITHELIAL CELL LINES THE UNITED STATES OF AMERICA, REPRESENTED BY THE SECRETARY, UNITED STATES DEPARTMENT OF COMMERCE (US) 1991-04-18 WO disclosed
US-4053317-A N-NITROSO COMPOUND, PHOTOPOLYMERIZABLE COMPOUND TEIJIN LIMITED (JA) 1977-10-11 US disclosed
US-3957823-A METALLIZATION BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-05-18 US disclosed