Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.34 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.34 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | G6PC1 | P35575 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439867 | 0.85 | NPC1 (0.36) | ALDH1A1TSHRCA2DDB1CRBN | |
| SCHEMBL15439801 | 0.85 | NPC1 (0.36) | ALDH1A1TSHRCA2DDB1CRBN | |
| SCHEMBL15439854 | 0.83 | MEN1 (0.37) | ALDH1A1TSHRCA2DDB1CRBN | |
| SCHEMBL15439643 | 0.81 | MAOB (0.34) | ALDH1A1TSHRCA2DDB1CRBN | |
| SCHEMBL15438614 | 0.80 | G6PC1 (0.33) | ALDH1A1TSHRCA2DDB1CRBN | |
| SCHEMBL15438966 | 0.80 | TSHR (0.42) | ALDH1A1TSHRCA2DDB1CRBN | |
| SCHEMBL15439235 | 0.79 | G6PC1 (0.46) | ALDH1A1TSHRCA2DDB1CRBN | |
| SCHEMBL15440546 | 0.78 | ALDH1A1 (0.47) | ALDH1A1NPC1RAB9AGAALMNA | |
| SCHEMBL15440232 | 0.77 | G6PC1 (0.41) | ALDH1A1TSHRCA2DDB1CRBN | |
| SCHEMBL15440176 | 0.77 | MAPT (0.40) | ALDH1A1TSHRCA2DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |