Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439737 | 1.00 | NPC1 (0.50) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15439860 | 0.92 | KMT2A (0.49) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15439856 | 0.92 | KMT2A (0.49) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15439230 | 0.86 | TDP1 (0.53) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15439231 | 0.86 | TDP1 (0.53) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15439289 | 0.84 | L3MBTL1 (0.55) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15439291 | 0.84 | L3MBTL1 (0.55) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15440538 | 0.84 | TDP1 (0.48) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15440539 | 0.84 | TDP1 (0.48) | NPC1RAB9ATDP1CASP3SENP8 | |
| SCHEMBL15439096 | 0.83 | G6PC1 (0.46) | NPC1RAB9AL3MBTL1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |