Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | CASP3 | P42574 | 1/20 | 0.48 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.48 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.48 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 5/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.42 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15440538 | 1.00 | TDP1 (0.48) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL15439406 | 0.92 | NR4A2 (0.44) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL15439405 | 0.92 | NR4A2 (0.44) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL14799479 | 0.92 | G6PC1 (0.45) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL14799480 | 0.92 | G6PC1 (0.45) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL14799602 | 0.86 | G6PC1 (0.47) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL14799601 | 0.86 | G6PC1 (0.47) | NPC1RAB9AMAPTKMT2AMEN1 | |
| SCHEMBL15439737 | 0.84 | NPC1 (0.50) | TDP1NPC1RAB9ACASP3SENP8 | |
| SCHEMBL15440268 | 0.84 | G6PC1 (0.44) | NPC1RAB9ALMNAMAPTKMT2A | |
| SCHEMBL15439734 | 0.84 | NPC1 (0.50) | TDP1NPC1RAB9ACASP3SENP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |