Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | GLA | P06280 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.33 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15439781 | 1.00 | TP53 (0.43) | TP53ALDH1A1TSHRGLACES2 | |
| SCHEMBL15440400 | 0.88 | ALDH1A1 (0.39) | TP53ALDH1A1TSHRGLACES2 | |
| SCHEMBL15440398 | 0.88 | ALDH1A1 (0.39) | TP53ALDH1A1TSHRGLACES2 | |
| SCHEMBL14799625 | 0.87 | TP53 (0.37) | TP53ALDH1A1TSHRGLACES2 | |
| SCHEMBL14799627 | 0.87 | TP53 (0.37) | TP53ALDH1A1TSHRGLACES2 | |
| SCHEMBL15439512 | 0.82 | TP53 (0.43) | TP53ALDH1A1TSHRGLACES2 | |
| SCHEMBL15439514 | 0.82 | TP53 (0.43) | TP53ALDH1A1TSHRGLACES2 | |
| SCHEMBL14799591 | 0.79 | ALDH1A1 (0.36) | TP53ALDH1A1TSHRGLAMAPT | |
| SCHEMBL14799594 | 0.79 | ALDH1A1 (0.36) | TP53ALDH1A1TSHRGLAMAPT | |
| SCHEMBL15440016 | 0.79 | CES2 (0.40) | TP53ALDH1A1TSHRGLACES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9115231-B2 | Polymers functionalized with protected hydrazone compounds containing an acyl group | BRIDGESTONE CORPORATION (JP) | 2015-08-25 | — | — | US | disclosed |
| US-20140031488-A1 | Polymers Functionalized With Protected Hydrazone Compounds Containing An Acyl Group | BRIDGESTONE CORPORATION (JP) | 2014-01-30 | — | — | US | disclosed |