Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.43 |
| ▸ | RAB9A | P51151 | 7/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | PRNP | P04156 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.39 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6200108 | 0.74 | ALDH1A1 (0.61) | SMN1; SMN2MEN1KMT2AMAPTGAA | |
| SCHEMBL15436050 | 0.73 | XDH (0.45) | — | |
| SCHEMBL15436051 | 0.73 | XDH (0.45) | — | |
| SCHEMBL16941668 | 0.72 | XDH (0.38) | NPC1RAB9ASMN1; SMN2PRNPMEN1 | |
| SCHEMBL27776363 | 0.71 | MEN1 (0.77) | NPC1RAB9ASMN1; SMN2MEN1KMT2A | |
| SCHEMBL28033321 | 0.70 | GAA (0.51) | RAB9AMAPTGAAALDH1A1CCNA2 | |
| SCHEMBL15445189 | 0.69 | NPC1 (0.37) | NPC1RAB9ASMN1; SMN2PRNPMEN1 | |
| SCHEMBL20142508 | 0.69 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2PRNPMEN1 | |
| SCHEMBL10957016 | 0.68 | NPC1 (0.51) | NPC1RAB9ASMN1; SMN2PRNPMEN1 | |
| SCHEMBL13941286 | 0.68 | ALDH1A1 (0.53) | NPC1RAB9ASMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2690105-A1 | Mannose derivatives, a process for preparing the same and their uses as a drug | Centre National De La Recherche Scientifique (FR) | 2014-01-29 | — | — | EP | disclosed |