Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.37 |
| ▸ | RAB9A | P51151 | 8/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.37 |
| ▸ | PRNP | P04156 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 8/20 | 0.36 |
| ▸ | MAPK13 | O15264 | 2/20 | 0.35 |
| ▸ | MAPK12 | P53778 | 2/20 | 0.35 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445145 | 0.69 | NPC1 (0.43) | NPC1RAB9ASMN1; SMN2PRNPCYP1A2 | |
| SCHEMBL15436010 | 0.67 | TSHR (0.44) | — | |
| SCHEMBL16946211 | 0.67 | TSHR (0.44) | — | |
| SCHEMBL16941671 | 0.67 | TSHR (0.44) | — | |
| SCHEMBL15436011 | 0.67 | TSHR (0.44) | — | |
| SCHEMBL28033321 | 0.67 | GAA (0.51) | RAB9AMAPTL3MBTL1CCNA2CDK2 | |
| SCHEMBL15445143 | 0.66 | NPC1 (0.41) | NPC1RAB9ASMN1; SMN2PRNPCYP1A2 | |
| SCHEMBL20953407 | 0.65 | LGALS3 (0.41) | NPC1RAB9ASMN1; SMN2PRNPMAPT | |
| SCHEMBL20142508 | 0.65 | NPC1 (0.44) | NPC1RAB9ASMN1; SMN2PRNPCYP1A2 | |
| SCHEMBL20953445 | 0.61 | NPC1 (0.40) | NPC1RAB9ASMN1; SMN2PRNPCYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2690105-A1 | Mannose derivatives, a process for preparing the same and their uses as a drug | Centre National De La Recherche Scientifique (FR) | 2014-01-29 | — | — | EP | disclosed |