Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGKA | P23743 | 2/20 | 0.45 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.40 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | NAAA | Q02083 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAD52 | P43351 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445494 | 0.85 | DGKA (0.47) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL19343643 | 0.84 | DGKA (0.55) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL16248011 | 0.82 | DGKA (0.47) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL7931889 | 0.81 | DGKA (0.43) | DGKATSHRALDH1A1CYP3A4ALOX15 | |
| SCHEMBL14028856 | 0.79 | THRB (0.59) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL7796142 | 0.79 | NAAA (0.60) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL21841359 | 0.79 | NAAA (0.60) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL15445481 | 0.78 | DGKA (0.48) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL6906132 | 0.78 | DGKA (0.69) | DGKAPRSS1PRSS2PRSS3DNM1 | |
| SCHEMBL23983091 | 0.77 | NAAA (0.57) | DGKAPRSS1PRSS2PRSS3DNM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9250356-B2 | Photochromic polymers | VIVIMED LABS EUROPE LTD (GB) | 2016-02-02 | — | — | US | disclosed |
| US-20140027684-A1 | PHOTOCHROMIC POLYMERS | VIVIMED LABS EUROPE LTD (GB) | 2014-01-30 | — | — | US | disclosed |