SCHEMBL154456

SCHEMBL154456

CCCCCCCCCCOC(=O)C(CCCCCC)CCCC(=O)O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FFAR4 Q5NUL3 2/20 0.54
FFAR1 O14842 2/20 0.54
GPR84 Q9NQS5 7/20 0.52
PPARG P37231 7/20 0.52
PPARD Q03181 7/20 0.52
PPARA Q07869 7/20 0.52
HDAC11 Q96DB2 5/20 0.52
TSHR P16473 4/20 0.52
PTPN1 P18031 3/20 0.52
ALDH1A1 P00352 2/20 0.52
TLR2 O60603 2/20 0.52
TDP1 Q9NUW8 2/20 0.52
FABP4 P15090 2/20 0.52
KMT2A Q03164 2/20 0.52
SLC22A6 Q4U2R8 1/20 0.52
SLC22A8 Q8TCC7 1/20 0.52
MEN1 O00255 1/20 0.52
ESR1 P03372 1/20 0.52
ALOX15 P16050 1/20 0.52
PDE4A P27815 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14672321 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL14672573 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL27674244 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL30725650 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL1445015 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL300447 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL29710707 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL6136050 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL4622335 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD
SCHEMBL9446481 1.00 FFAR4 (0.54) FFAR4FFAR1GPR84PPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 193 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118284400-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-07-02 CN disclosed
CN-118284399-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-07-02 CN disclosed
CN-118265517-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-06-28 CN disclosed
CN-118234468-A Cosmetic product 株式会社资生堂 2024-06-21 CN disclosed
CN-118215462-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-06-18 CN disclosed
CN-118201596-A Cosmetic product 株式会社资生堂 2024-06-14 CN disclosed
CN-118175985-A Oil-in-water type emulsified cosmetic 株式会社资生堂 2024-06-11 CN disclosed
CN-114641274-B Oil-in-water type composition 株式会社资生堂 2024-06-04 CN disclosed
CN-118076336-A Water-in-oil type emulsified cosmetic 株式会社资生堂 2024-05-24 CN disclosed
CN-118019518-A Water-in-oil type emulsified cosmetic 株式会社资生堂 2024-05-10 CN disclosed
US-20040146472-A1 Polyhydric alcohol-modified silicone and cosmetic material containing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-07-29 US disclosed
EP-1430905-A1 EXTERNAL PREPARATION FOR THE SKIN SHISEIDO COMPANY LIMITED (JP) 2004-06-23 EP disclosed
EP-1415639-A1 COMETICS AND MAKEUP METHOD Kanebo, Limited (JP) 2004-05-06 EP disclosed
US-20030158363-A1 Odorless modified silicone compound,cosmetic preparation containing the same, and method of purifying modified silicone compound having branch polymer comprising hydrophilic group SHIN-ETSU CHEMICAL CO., LTD. (JP) 2003-08-21 US disclosed
US-6607736-B2 Endermic liniment comprising diethoxy ethyl succinate and humectant SHISEIDO COMPANY, LTD. (JP) 2003-08-19 US disclosed
US-20030091603-A1 Skin preparations for external use SHISEIDO COMPANY, LTD. (JP) 2003-05-15 US disclosed
CN-1394138-A Hair growth agent SHISEIDO CO LTD (JP) 2003-01-29 CN disclosed
US-20020131947-A1 Polyhydric alcohol-modified silicone and cosmetic material containing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-09-19 US disclosed
EP-1213316-A2 Polyhydric alcohol-modified silicone and cosmetic material containing same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2002-06-12 EP disclosed
EP-1153602-A1 SKIN PREPARATIONS FOR EXTERNAL USE SHISEIDO COMPANY LIMITED (JP) 2001-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040146472-A1 Polyhydric alcohol-modified silicone and cosmetic material containing same H1-0, H1-2, H1-3 FFAR4 378/4885FFAR1 101/4885GPR84 241/4885
US-20030091603-A1 Skin preparations for external use CUTA, POLR1C, ACMSD FFAR4 1067/4885FFAR1 140/4885GPR84 795/4885
US-20020131947-A1 Polyhydric alcohol-modified silicone and cosmetic material containing same H1-0, H1-2, H1-3 FFAR4 378/4885FFAR1 101/4885GPR84 241/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.