Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.36 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.36 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTR1F | P30939 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15445726 | 0.95 | TAS1R3 (0.34) | TAS1R3TAS1R1TAS1R2SMN1; SMN2KDM4E | |
| SCHEMBL15445706 | 0.86 | HPGD (0.37) | TAS1R3TAS1R1TAS1R2SMN1; SMN2KDM4E | |
| SCHEMBL15445707 | 0.86 | TAS1R3 (0.36) | TAS1R3TAS1R1TAS1R2SMN1; SMN2KDM4E | |
| SCHEMBL15445736 | 0.83 | — | — | |
| SCHEMBL15446031 | 0.83 | KMT2A (0.30) | KMT2A | |
| SCHEMBL15445729 | 0.83 | HPGD (0.35) | TAS1R3TAS1R1TAS1R2SMN1; SMN2KDM4E | |
| SCHEMBL15445724 | 0.83 | TAS1R3 (0.34) | TAS1R3TAS1R1TAS1R2SMN1; SMN2KDM4E | |
| SCHEMBL15445714 | 0.81 | ALDH1A1 (0.33) | TAS1R3TAS1R1TAS1R2KDM4EALDH1A1 | |
| SCHEMBL15446003 | 0.80 | MGLL (0.32) | TAS1R3TAS1R1TAS1R2ALDH1A1MGLL | |
| SCHEMBL15445713 | 0.79 | TAS1R3 (0.33) | TAS1R3TAS1R1TAS1R2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140028964-A1 | LIQUID-CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2014-01-30 | — | — | US | disclosed |