SCHEMBL15453003

SCHEMBL15453003

CCN(C)c1ccc(N)c(C)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
S100B P04271 1/20 0.69
IGLV6-57 P01721 1/20 0.45
ALDH1A1 P00352 7/20 0.45
CYP3A4 P08684 7/20 0.45
TDP1 Q9NUW8 7/20 0.45
TSHR P16473 4/20 0.45
SKP2 Q13309 1/20 0.43
ADRA2A P08913 1/20 0.42
ADRA2B P18089 1/20 0.42
ADRA2C P18825 1/20 0.42
ESR1 P03372 2/20 0.40
AR P10275 1/20 0.40
ESR2 Q92731 1/20 0.40
APAF1 O14727 1/20 0.39
MAPK1 P28482 3/20 0.38
RECQL P46063 2/20 0.38
GAA P10253 1/20 0.38
RAD52 P43351 1/20 0.38
PSMD14 O00487 1/20 0.38
GFER P55789 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29740664 0.86 S100B (0.60) S100BALDH1A1CYP3A4TDP1TSHR
SCHEMBL10955324 0.86 S100B (0.60) S100BALDH1A1CYP3A4TDP1TSHR
SCHEMBL15928738 0.84 S100B (0.48) S100BIGLV6-57ALDH1A1CYP3A4TDP1
SCHEMBL34104 0.82 S100B (1.00) S100BIGLV6-57ALDH1A1CYP3A4TDP1
SCHEMBL29350181 0.82 S100B (1.00) S100BIGLV6-57ALDH1A1CYP3A4TDP1
SCHEMBL13412501 0.81 IGLV6-57 (0.49) S100BIGLV6-57ALDH1A1ADRA2AADRA2B
SCHEMBL16003239 0.81 S100B (0.55) S100BALDH1A1CYP3A4TDP1TSHR
Hydrochloric Acid SCHEMBL3385174 0.80 S100B (0.96) S100BIGLV6-57ALDH1A1CYP3A4TDP1
Hydrochloric Acid SCHEMBL2136137 0.80 S100B (0.96) S100BIGLV6-57ALDH1A1CYP3A4TDP1
SCHEMBL5550263 0.79 S100B (0.53) S100BALDH1A1CYP3A4TDP1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2692728-A1 NOVEL FURANONE DERIVATIVE SBI Biotech Co., Ltd. (JP) 2014-02-05 EP disclosed