SCHEMBL15460201

SCHEMBL15460201

CC1(C)c2ccccc2-c2cc3c(-c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc4c5cc(-c6ccc7c(c6)c6ccccc6n7-c6ccccc6)c6cc7c(cc6c5oc4c3cc21)C(C)(C)c1ccccc1-7

nearest known ligand 0.38

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.38
ATM Q13315 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
PTGER4 P35408 1/20 0.31
MEN1 O00255 1/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
TSHR P16473 1/20 0.31
BRCA1 P38398 1/20 0.31
KMT2A Q03164 1/20 0.31
HSD17B10 Q99714 1/20 0.31
PGR P06401 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460233 0.90 KDM4E (0.36) KDM4EATML3MBTL1PTGER4
SCHEMBL14725784 0.88 KDM4E (0.38) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL15460277 0.88 KDM4E (0.38) KDM4EATML3MBTL1PTGER4PGR
SCHEMBL13152958 0.87 KDM4E (0.43) KDM4EATML3MBTL1PTGER4KMT2A
SCHEMBL15338025 0.86 L3MBTL1 (0.44) KDM4EATML3MBTL1PTGER4MEN1
SCHEMBL15946303 0.86 L3MBTL1 (0.44) KDM4EATML3MBTL1PTGER4MEN1
SCHEMBL10001493 0.86 L3MBTL1 (0.44) KDM4EATML3MBTL1PTGER4MEN1
SCHEMBL29694589 0.86 L3MBTL1 (0.44) KDM4EATML3MBTL1PTGER4MEN1
SCHEMBL22807771 0.85 ALOX5 (0.36) KDM4EATML3MBTL1
SCHEMBL15460317 0.85 KDM4E (0.35) KDM4EATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed