SCHEMBL15460211

SCHEMBL15460211

c1ccc2c(c1)oc1ccc3c4oc5c(cc(-c6cccc7c6sc6ccccc67)c6c5ccc5oc7ccccc7c56)c4cc(-c4cccc5c4sc4ccccc45)c3c12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 2/20 0.40
PRKDC P78527 9/20 0.40
PIK3CD O00329 2/20 0.40
PIK3CB P42338 2/20 0.40
BRD4 O60885 1/20 0.40
PIK3CA P42336 1/20 0.40
MTOR P42345 1/20 0.40
PIK3CG P48736 1/20 0.40
KCNH2 Q12809 1/20 0.40
BRDT Q58F21 1/20 0.40
PARP14 Q460N5 1/20 0.38
ESR2 Q92731 2/20 0.35
ESR1 P03372 1/20 0.34
HTT P42858 1/20 0.32
PAX8 Q06710 1/20 0.32
MAPT P10636 2/20 0.32
GPR3 P46089 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460289 0.90 ALOX5 (0.42) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL20821582 0.81 PARP14 (0.47) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15460185 0.81 ALOX5 (0.50) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL19076597 0.80 ALOX5 (0.40) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL24519056 0.80 PRKDC (0.39) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15460222 0.79 ALOX5 (0.50) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL15460352 0.79 PRKDC (0.36) PRKDCMAPTKDM4EMEN1ALDH1A1
SCHEMBL24518949 0.77 PRKDC (0.46) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL25631039 0.77 ALOX5 (0.45) ALOX5PRKDCPIK3CDPIK3CBBRD4
SCHEMBL17930627 0.77 GPR3 (0.45) ALOX5PRKDCESR2ESR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed