SCHEMBL15460352

SCHEMBL15460352

c1ccc2c(c1)oc1ccc3c4oc5c(cc(-c6csc7ccccc67)c6c5ccc5oc7ccccc7c56)c4cc(-c4csc5ccccc45)c3c12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.36
ERN1 O75460 2/20 0.35
ATM Q13315 1/20 0.33
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 3/20 0.33
MAPT P10636 3/20 0.33
HPGD P15428 3/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
AHR P35869 2/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
APP P05067 2/20 0.32
CYP2C9 P11712 1/20 0.32
MAOB P27338 2/20 0.32
CHRM2 P08172 1/20 0.32
CHRM4 P08173 1/20 0.32
CHRM5 P08912 1/20 0.32
CHRM1 P11229 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460357 0.87 PRKDC (0.34) PRKDCERN1ATMKDM4EALDH1A1
SCHEMBL15460178 0.80 ERN1 (0.43) PRKDCERN1ATMALDH1A1MAPT
SCHEMBL15460211 0.79 ALOX5 (0.40) PRKDCKDM4EALDH1A1MAPTMEN1
SCHEMBL15460249 0.77 PRKDC (0.40) PRKDCERN1ATMMAPTHPGD
SCHEMBL15460209 0.75 MAPT (0.42) KDM4EALDH1A1MAPTHPGDMEN1
SCHEMBL15460241 0.73 AHR (0.41) PRKDCERN1ATMKDM4EALDH1A1
SCHEMBL14725729 0.73 PRKDC (0.35) PRKDCERN1ATMKDM4EALDH1A1
SCHEMBL26266632 0.72 ERN1 (0.37) PRKDCERN1ATMKDM4EALDH1A1
SCHEMBL14883076 0.70 PRKDC (0.35) PRKDCERN1ATMKDM4EALDH1A1
SCHEMBL15460205 0.70 CYP11B1 (0.43) PRKDCKDM4EALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed