SCHEMBL15460280

SCHEMBL15460280

c1ccc2c(-c3cc4c5cc(-c6csc7ccccc67)c6ccsc6c5sc4c4sccc34)csc2c1

nearest known ligand 0.38

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CYP2A6 P11509 3/20 0.38
ERN1 O75460 4/20 0.37
APP P05067 2/20 0.36
CHRM2 P08172 1/20 0.35
CHRM4 P08173 1/20 0.35
CHRM5 P08912 1/20 0.35
CHRM1 P11229 1/20 0.35
CHRM3 P20309 1/20 0.35
CYP2C9 P11712 1/20 0.35
PRKDC P78527 3/20 0.35
MAPT P10636 1/20 0.34
ALDH1A1 P00352 2/20 0.33
HPGD P15428 1/20 0.33
MAOB P27338 1/20 0.33
ATM Q13315 1/20 0.32
HDAC2 Q92769 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460256 0.85 ERN1 (0.41) CYP2A6ERN1APPCHRM2CHRM4
SCHEMBL15460323 0.83 ERN1 (0.36) CYP2A6ERN1APPCHRM2CHRM4
SCHEMBL15460190 0.82 PRKDC (0.41) CYP2A6ERN1APPCHRM2CHRM4
SCHEMBL15460278 0.79 ALOX5 (0.47) PRKDCMAPTALDH1A1HPGDATM
SCHEMBL15460232 0.79 PRKDC (0.39) CYP2A6ERN1APPCHRM2CHRM4
SCHEMBL4381193 0.75 CYP2A6 (0.54) CYP2A6ERN1APPCHRM2CHRM4
SCHEMBL15460264 0.74 CYP11B1 (0.37) CYP2A6ERN1APPALDH1A1HPGD
SCHEMBL15460282 0.73 APP (0.33) ERN1APPCHRM2CHRM4CHRM5
SCHEMBL15460306 0.71 MAPT (0.43) CYP2A6ERN1APPCHRM2CHRM4
SCHEMBL15460178 0.70 ERN1 (0.43) CYP2A6ERN1APPCHRM2CHRM4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed