SCHEMBL15460232

SCHEMBL15460232

c1ccc2c(-c3cc4oc5cc(-c6csc7ccccc67)c6ccsc6c5c4c4sccc34)csc2c1

nearest known ligand 0.39

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
PRKDC P78527 2/20 0.39
ATM Q13315 1/20 0.36
ERN1 O75460 3/20 0.35
APP P05067 2/20 0.34
MAOB P27338 3/20 0.34
CHRM2 P08172 1/20 0.34
CHRM4 P08173 1/20 0.34
CHRM5 P08912 1/20 0.34
CHRM1 P11229 1/20 0.34
CHRM3 P20309 1/20 0.34
CYP2C9 P11712 1/20 0.34
ACVRL1 P37023 1/20 0.34
ACVR1 Q04771 1/20 0.34
CYP2A6 P11509 3/20 0.33
KDM1A O60341 1/20 0.33
MAPT P10636 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15460249 0.84 PRKDC (0.40) PRKDCATMERN1APPMAOB
SCHEMBL15460323 0.84 ERN1 (0.36) PRKDCERN1APPMAOBCHRM2
SCHEMBL15460190 0.82 PRKDC (0.41) PRKDCATMERN1APPMAOB
SCHEMBL15460238 0.79 ALOX5 (0.44) PRKDCMAPT
SCHEMBL15460280 0.79 CYP2A6 (0.38) PRKDCATMERN1APPMAOB
SCHEMBL15460241 0.74 AHR (0.41) PRKDCATMERN1APPMAOB
SCHEMBL15460354 0.73 MAP3K7 (0.41) PRKDCATMMAOBACVRL1ACVR1
SCHEMBL15460246 0.73 PRKDC (0.33) PRKDCATMERN1APPMAOB
SCHEMBL4381193 0.73 CYP2A6 (0.54) ERN1APPMAOBCHRM2CHRM4
SCHEMBL15460234 0.72 MAPT (0.45) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9385327-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG DISPLAY CO., LTD. (KR) 2016-07-05 US disclosed
US-9349966-B2 2016-05-24 US disclosed
US-20140034915-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG DISPLAY CO. LTD. (KR) 2014-02-06 US disclosed