Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.54 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.50 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.50 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.50 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.50 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.50 |
| ▸ | ERN1 | O75460 | 2/20 | 0.47 |
| ▸ | GPR3 | P46089 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.45 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.45 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.45 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.45 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.45 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.45 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.45 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.45 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5848721 | 0.85 | CYP2A6 (0.52) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL31092063 | 0.85 | CYP2A6 (0.52) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL23555986 | 0.85 | ERN1 (0.54) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL20174709 | 0.85 | CYP2A6 (0.42) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL9729982 | 0.85 | CYP2A6 (0.42) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL14451018 | 0.85 | CYP2A6 (0.47) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL398176 | 0.85 | ALDH1A1 (0.52) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL9787033 | 0.85 | CNR2 (0.49) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL13319555 | 0.83 | ERN1 (0.42) | CYP2A6MAPTCHRM2CHRM4CHRM5 | |
| SCHEMBL13408716 | 0.83 | ERN1 (0.42) | CYP2A6MAPTCHRM2CHRM4CHRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2015177763-A9 | ELECTRO-ACTIVE MACROCYCLIC OLIGOARENES AND OLIGOHETEROARENES WITH STEREOGENIC AXES | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2016-01-21 | — | — | WO | claimed |
| WO-2015177763-A1 | ELECTRO-ACTIVE MACROCYCLIC OLIGOARENES AND OLIGOHETEROARENES WITH STEREOGENIC AXES | UNIVERSITA' DEGLI STUDI DI MILANO (IT) | 2015-11-26 | — | — | WO | claimed |
| US-6077958-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 2000-06-20 | — | — | US | claimed |
| EP-0770085-B1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI SPA (IT) | 1999-09-22 | — | — | EP | claimed |
| US-5907045-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 1999-05-25 | — | — | US | claimed |
| EP-0770085-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.p.A. (IT) | 1997-05-02 | — | — | EP | claimed |
| WO-1996001831-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.P.A. (IT) | 1996-01-25 | — | — | WO | claimed |
| US-10749117-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2020-08-18 | — | — | US | disclosed |
| US-9893297-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2018-02-13 | — | — | US | disclosed |
| US-9893297-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2018-02-13 | — | — | US | disclosed |
| US-9893297-B2 | Materials for electronic devices | MERCK PATENT GMBH (DE) | 2018-02-13 | — | — | US | disclosed |
| US-20170104165-A1 | MATERIALS FOR ELECTRONIC DEVICES | UDC IRELAND LIMITED (IE) | 2017-04-13 | — | — | US | disclosed |
| US-20170104165-A1 | MATERIALS FOR ELECTRONIC DEVICES | UDC IRELAND LIMITED (IE) | 2017-04-13 | — | — | US | disclosed |
| US-6297387-B1 | AND THEIR USE AS CHIRAL CATALYSTS IN STEREOCONTROLLED REACTIONS, SUCH AS DIASTEREO- AND ENANTIOSELECTIVE REDUCTION REACTIONS, | ITALFARMACO SUD S.P.A. (IT) | 2001-10-02 | — | — | US | disclosed |
| US-6133191-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 2000-10-17 | — | — | US | disclosed |
| US-6077958-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 2000-06-20 | — | — | US | disclosed |
| EP-0770085-B1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | CHEMI SPA (IT) | 1999-09-22 | — | — | EP | disclosed |
| US-5907045-A | Heteroaromatic diphosphines as chiral ligands | ITALFARMACO SUD S.P.A. (IT) | 1999-05-25 | — | — | US | disclosed |
| EP-0770085-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.p.A. (IT) | 1997-05-02 | — | — | EP | disclosed |
| WO-1996001831-A1 | HETEROAROMATIC DIPHOSPHINES AS CHIRAL LIGANDS | ITALFARMACO SUD S.P.A. (IT) | 1996-01-25 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170104165-A1 | MATERIALS FOR ELECTRONIC DEVICES | EFNA1, CYP2C19, SDHB | CYP2A6 241/4885MAPT 2005/4885CHRM2 924/4885 |
| US-10749117-B2 | Materials for electronic devices | EFNA1, CYP2C19, SDHB | CYP2A6 241/4885MAPT 2005/4885CHRM2 924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.