Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 0.56 |
| ▸ | CXCL12 | P48061 | 1/20 | 0.56 |
| ▸ | MAOB | P27338 | 1/20 | 0.56 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.55 |
| ▸ | HSP90AB1 | P08238 | 2/20 | 0.55 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.47 |
| ▸ | TUBB4A | P04350 | 5/20 | 0.42 |
| ▸ | TUBB | P07437 | 5/20 | 0.42 |
| ▸ | TUBA3C | P0DPH7 | 5/20 | 0.42 |
| ▸ | TUBA1B | P68363 | 5/20 | 0.42 |
| ▸ | TUBA4A | P68366 | 5/20 | 0.42 |
| ▸ | TUBB4B | P68371 | 5/20 | 0.42 |
| ▸ | TUBB3 | Q13509 | 5/20 | 0.42 |
| ▸ | TUBB2A | Q13885 | 5/20 | 0.42 |
| ▸ | TUBB8 | Q3ZCM7 | 5/20 | 0.42 |
| ▸ | TUBA3E | Q6PEY2 | 5/20 | 0.42 |
| ▸ | TUBA1A | Q71U36 | 5/20 | 0.42 |
| ▸ | TUBA1C | Q9BQE3 | 5/20 | 0.42 |
| ▸ | TUBB6 | Q9BUF5 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12687343 | 0.87 | MAOA (0.60) | MAOACXCL12MAOBHSP90AA1HSP90AB1 | |
| SCHEMBL30837237 | 0.81 | CXCL12 (0.83) | MAOACXCL12MAOBHSP90AA1HSP90AB1 | |
| SCHEMBL15425075 | 0.81 | MAOA (0.67) | MAOACXCL12MAOBHSP90AA1HSP90AB1 | |
| SCHEMBL16508311 | 0.80 | MAOA (0.69) | MAOACXCL12MAOBHSP90AA1HSP90AB1 | |
| SCHEMBL15460411 | 0.77 | PTPN1 (0.45) | MAOBPTGS2MAPTALDH1A1HPGD | |
| SCHEMBL15425082 | 0.76 | HSP90AA1 (0.65) | MAOACXCL12MAOBHSP90AA1HSP90AB1 | |
| SCHEMBL22731736 | 0.76 | HSP90AA1 (0.59) | MAOACXCL12MAOBHSP90AA1HSP90AB1 | |
| SCHEMBL12687428 | 0.73 | MAOB (0.61) | MAOAMAOBPTGS2MAPT | |
| SCHEMBL30837175 | 0.72 | CXCL12 (1.00) | MAOACXCL12MAOBHSP90AA1HSP90AB1 | |
| SCHEMBL15425077 | 0.72 | HSP90AA1 (0.70) | MAOACXCL12MAOBHSP90AA1HSP90AB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102638-B2 | Amidobenzothiazoles and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-08-11 | — | — | US | disclosed |
| US-8921552-B2 | Benzothiazole hybrids useful as anticancer agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-30 | — | — | US | disclosed |
| US-20140039190-A1 | BENZOTHIAZOLE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039190-A1 | BENZOTHIAZOLE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | TP53, MCL1, SDHA | MAOA 2223/4885CXCL12 4033/4885MAOB 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.