Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 2/20 | 0.45 |
| ▸ | MIF | P14174 | 4/20 | 0.43 |
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | XDH | P47989 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | KDM1A | O60341 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5686355 | 0.87 | TUBB4A (0.52) | PTPN1MIFMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL17366133 | 0.85 | TUBB4A (0.47) | PTPN1MIFCYP19A1TP53CYP3A4 | |
| SCHEMBL15460398 | 0.84 | PTPN1 (0.43) | PTPN1MIFMAOBMAPTSMN1; SMN2 | |
| SCHEMBL15460408 | 0.83 | PTPN1 (0.42) | PTPN1MIFMAOBMAPTSMN1; SMN2 | |
| SCHEMBL13643398 | 0.80 | PTPN1 (0.43) | PTPN1MIFMAOBCYP19A1TP53 | |
| SCHEMBL15463035 | 0.79 | MAPT (0.48) | PTPN1MIFMAOBMAPTSMN1; SMN2 | |
| SCHEMBL13660015 | 0.78 | MIF (0.51) | PTPN1MIFMAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL15460410 | 0.77 | MAOA (0.56) | MAOBMAPTHPGDALDH1A1PTGS2 | |
| SCHEMBL5689279 | 0.75 | TUBB4A (0.49) | PTPN1MIFMAPTHSD17B10IARS1 | |
| SCHEMBL16602594 | 0.75 | DRD2 (0.37) | PTPN1MIFMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9102638-B2 | Amidobenzothiazoles and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-08-11 | — | — | US | disclosed |
| US-8921552-B2 | Benzothiazole hybrids useful as anticancer agents and process for the preparation thereof | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-12-30 | — | — | US | disclosed |
| US-20140039190-A1 | BENZOTHIAZOLE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140039190-A1 | BENZOTHIAZOLE HYBRIDS USEFUL AS ANTICANCER AGENTS AND PROCESS FOR THE PREPARATION THEREOF | TP53, MCL1, SDHA | PTPN1 4424/4885MIF 3592/4885MAOB 1683/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.