Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.83 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.30 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propylene Glycol SCHEMBL458673 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL2590009 | 1.00 | TDP1 (0.83) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL83155 | 1.00 | — | — | |
| Propylene Glycol SCHEMBL28149710 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL6131091 | 0.96 | — | — | |
| Propylene Glycol SCHEMBL23928058 | 0.93 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL8851421 | 0.93 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL8851046 | 0.93 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL3359837 | 0.93 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNAL3MBTL1 | |
| Propylene Glycol SCHEMBL5483468 | 0.93 | TDP1 (0.71) | TDP1TSHRALDH1A1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11325362-B2 | Layered polyester film | TOYOBO CO., LTD. (JP) | 2022-05-10 | — | — | US | disclosed |
| US-20200289556-A1 | METALLIC COPPER FINE PARTICLES AND METHOD FOR PRODUCING THE SAME | TOYO SEIKAN GROUP HOLDINGS, LTD. (JP) | 2020-09-17 | — | — | US | disclosed |
| US-20200269560-A1 | LAYERED POLYESTER FILM | TOYOBO CO., LTD. (JP) | 2020-08-27 | — | — | US | disclosed |
| US-9709909-B2 | Electrostatic latent image developing toner | KYOCERA DOCUMENT SOLUTIONS INC. (JP) | 2017-07-18 | — | — | US | disclosed |
| US-9383669-B2 | Brilliant toner, developer, toner cartridge, process cartridge, and image forming apparatus | FUJI XEROX CO., LTD. (JP) | 2016-07-05 | — | — | US | disclosed |
| US-20140045113-A1 | BRILLIANT TONER, DEVELOPER, TONER CARTRIDGE, PROCESS CARTRIDGE, AND IMAGE FORMING APPARATUS | FUJI XEROX CO., LTD. (JP) | 2014-02-13 | — | — | US | disclosed |