Propylene Glycol

Propylene Glycol

SCHEMBL2590009

C=C.C=C.C=C.C=C.CC(O)CO

nearest known ligand 0.83

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

SLC5A2

The experimentally established mechanism targets of Propylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.83
TSHR P16473 4/20 0.50
ALDH1A1 P00352 3/20 0.44
LMNA P02545 4/20 0.40
L3MBTL1 Q9Y468 1/20 0.35
MAPK1 P28482 1/20 0.32
THRB P10828 1/20 0.32
HSD17B10 Q99714 1/20 0.30
OR51E2 Q9H255 1/20 0.30
AKR1B1 P15121 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propylene Glycol SCHEMBL458673 1.00
Propylene Glycol SCHEMBL15463578 1.00 TDP1 (0.83) TDP1TSHRALDH1A1LMNAL3MBTL1
Propylene Glycol SCHEMBL83155 1.00
Propylene Glycol SCHEMBL28149710 0.96
Propylene Glycol SCHEMBL6131091 0.96
Propylene Glycol SCHEMBL23928058 0.93 TDP1 (0.71) TDP1TSHRALDH1A1LMNAL3MBTL1
Propylene Glycol SCHEMBL8851421 0.93 TDP1 (0.71) TDP1TSHRALDH1A1LMNAL3MBTL1
Propylene Glycol SCHEMBL8851046 0.93 TDP1 (0.71) TDP1TSHRALDH1A1LMNAL3MBTL1
Propylene Glycol SCHEMBL3359837 0.93 TDP1 (0.71) TDP1TSHRALDH1A1LMNAL3MBTL1
Propylene Glycol SCHEMBL5483468 0.93 TDP1 (0.71) TDP1TSHRALDH1A1LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2013081913-A1 TREATMENT OF RECYCLE GAS FROM ACID HYDROGENATION CELANESE INTERNATIONAL CORPORATION (US) 2013-06-06 WO disclosed
WO-2013070213-A1 IINTEGRATED PROCESS FOR PRODUCING ETHANOL FROM METHANOL WITH WATER BALANCE CONTROL CELANESE INTERNATIONAL CORPORATION (US) 2013-05-16 WO disclosed
WO-2013070216-A1 INTEGRATED ETHANOL PRODUCTION FROM METHANOL VIA CARBONYLATION AND HYDROGENATION BY EXTRACTING HALIDES FROM ACETIC ACID CELANESE INTERNATIONAL CORPORATION (US) 2013-05-16 WO disclosed
WO-2013070212-A1 PRODUCING ETHANOL USING TWO DIFFERENT STREAMS FROM ACETIC ACID CARBONYLATION PROCESS CELANESE INTERNATIONAL CORPORATION (US) 2013-05-16 WO disclosed
WO-2013070211-A1 INTEGRATED PROCESS FOR PRODUCING ETHANOL FROM METHANOL CELANESE INTERNATIONAL CORPORATION (US) 2013-05-16 WO disclosed
EP-2566835-A1 PROCESS FOR PRODUCING ETHANOL Celanese International Corporation (US) 2013-03-13 EP disclosed
WO-2012149137-A1 PROCESS FOR THE PRODUCTION OF ETHANOL FROM AN ACETIC ACID FEED AND A RECYCLED ETHYL ACETATE FEED CELANESE INTERNATIONAL CORPORATION (US) 2012-11-01 WO disclosed
WO-2011140455-A1 PROCESS FOR PRODUCING ETHANOL CELANESE INTERNATIONAL CORPORATION (US) 2011-11-10 WO disclosed